



PEPXEN Biotechnologies supplies highly purified research peptides manufactured at GMP-certified facilities in Japan.
HPLC testing for every batch
Purity certificate with every shipment
From the lab to your door
Fast dispatch with tracking
Most requested research peptides.




Real experience from pepxen researchers.
How peptides work — clear, science-based explainers.

Retatrutide (LY3437943) is a triple-action research peptide developed by Eli Lilly. Unlike semaglutide (a GLP-1 agonist) and tirzepatide (a dual GLP-1/GIP agonist), retatrutide acts on three receptors at once: GLP-1, GIP, and the glucagon receptor (GCGR). It is this third component that makes it unique — glucagon directly stimulates the breakdown of fat stores and raises the body’s energy expenditure.

Mitochondria are the power plants of every cell. They produce ATP — the universal “currency” of energy in the body. With age, mitochondria lose efficiency: their DNA gets damaged, the electron transport chain malfunctions, and the production of free radicals increases. This process is called mitochondrial dysfunction, and it underlies most age-related diseases — from diabetes and neurodegeneration to sarcopenia and chronic fatigue.